All tests

Haematology

BCR/ABLBCR-ABL transcript (RT-qPCR)

Chronic myeloid leukaemia and Ph+ acute lymphoblastic leukaemia: diagnosis and monitoring under treatment.

Method
Quantitative RT-PCR
Accepted samples
Blood (EDTA), bone marrow
Price
Price on request
Turnaround
7 daysafter receipt of a compliant sample

What the test looks for

Detection and quantification of the BCR-ABL1 fusion transcript by quantitative RT-PCR.

At diagnosis, the test identifies the transcript type. During treatment with a tyrosine kinase inhibitor, the result is expressed as a percentage on the International Scale (BCR-ABL1/ABL1 IS) to assess the molecular response.

Required sample

  • Whole blood on EDTA: 2 tubes of 5 mL, or bone marrow on EDTA.
  • At room temperature, not frozen.
  • Must reach the laboratory within 24 hours of sampling.
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